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Solid-State Formation of a Potential Melphalan Delivery Nanosystem Based on β-Cyclodextrin and Silver Nanoparticles

Melphalan (Mel) is an antineoplastic widely used in cancer and other diseases. Its low solubility, rapid hydrolysis, and non-specificity limit its therapeutic performance. To overcome these disadvantages, Mel was included in β-cyclodextrin (βCD), which is a macromolecule that increases its aqueous s...

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Detalles Bibliográficos
Autores principales: Sierpe, Rodrigo, Donoso-González, Orlando, Lang, Erika, Noyong, Michael, Simon, Ulrich, Kogan, Marcelo J., Yutronic, Nicolás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964812/
https://www.ncbi.nlm.nih.gov/pubmed/36835401
http://dx.doi.org/10.3390/ijms24043990