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Cannabidiol-Loaded Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Paclitaxel-Induced Peripheral Neuropathy

In cancer patients, chronic paclitaxel (PTX) treatment causes excruciating pain, limiting its use in cancer chemotherapy. The neuroprotective potential of synthetic cannabidiol (CBD) and CBD formulated in extracellular vesicles (CBD-EVs) isolated from human umbilical cord derived mesenchymal stem ce...

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Detalles Bibliográficos
Autores principales: Kalvala, Anil Kumar, Bagde, Arvind, Arthur, Peggy, Kulkarni, Tanmay, Bhattacharya, Santanu, Surapaneni, Sunil, Patel, Nil Kumar, Nimma, Ramesh, Gebeyehu, Aragaw, Kommineni, Nagavendra, Meckes, Jr., David G., Sun, Li, Banjara, Bipika, Mosley-Kellum, Keb, Dinh, Thanh Cong, Singh, Mandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964872/
https://www.ncbi.nlm.nih.gov/pubmed/36839877
http://dx.doi.org/10.3390/pharmaceutics15020554