A Rapid and Sensitive UHPLC–MS/MS Method for Determination of Chlorogenic Acid and Its Application to Distribution and Neuroprotection in Rat Brain

Chlorogenic acid (5-CQA) is a phenolic natural product that has been reported to improve neurobehavioral disorders and brain injury. However, its pharmacokinetics and distribution in the rat brain remain unclear. In this study, we established a rapid and sensitive UHPLC–MS/MS method for the determin...

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Detalles Bibliográficos
Autores principales: Bai, Chongfei, Zhou, Xiaogang, Yu, Lu, Wu, Anguo, Yang, Le, Chen, Jianping, Tang, Xue, Zou, Wenjun, Wu, Jianming, Zhu, Linjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964875/
https://www.ncbi.nlm.nih.gov/pubmed/37259330
http://dx.doi.org/10.3390/ph16020178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964875/
https://www.ncbi.nlm.nih.gov/pubmed/37259330
http://dx.doi.org/10.3390/ph16020178

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