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A Rapid and Sensitive UHPLC–MS/MS Method for Determination of Chlorogenic Acid and Its Application to Distribution and Neuroprotection in Rat Brain

Chlorogenic acid (5-CQA) is a phenolic natural product that has been reported to improve neurobehavioral disorders and brain injury. However, its pharmacokinetics and distribution in the rat brain remain unclear. In this study, we established a rapid and sensitive UHPLC–MS/MS method for the determin...

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Detalles Bibliográficos
Autores principales:	Bai, Chongfei, Zhou, Xiaogang, Yu, Lu, Wu, Anguo, Yang, Le, Chen, Jianping, Tang, Xue, Zou, Wenjun, Wu, Jianming, Zhu, Linjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964875/ https://www.ncbi.nlm.nih.gov/pubmed/37259330 http://dx.doi.org/10.3390/ph16020178

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