An Engineered IFNγ-Antibody Fusion Protein with Improved Tumor-Homing Properties

Interferon-gamma (IFNγ) is one of the central cytokines produced by the innate and adaptive immune systems. IFNγ directly favors tumor growth control by enhancing the immunogenicity of tumor cells, induces IP-10 secretion facilitating (CXCR3+) immune cell infiltration, and can prime macrophages to a...

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Detalles Bibliográficos
Autores principales: Di Nitto, Cesare, Gilardoni, Ettore, Mock, Jacqueline, Nadal, Lisa, Weiss, Tobias, Weller, Michael, Seehusen, Frauke, Libbra, Chiara, Puca, Emanuele, Neri, Dario, De Luca, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964878/
https://www.ncbi.nlm.nih.gov/pubmed/36839699
http://dx.doi.org/10.3390/pharmaceutics15020377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964878/
https://www.ncbi.nlm.nih.gov/pubmed/36839699
http://dx.doi.org/10.3390/pharmaceutics15020377

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