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Betulinic Acid Inhibits the Stemness of Gastric Cancer Cells by Regulating the GRP78-TGF-β1 Signaling Pathway and Macrophage Polarization

Cancer stemness is the process by which cancer cells acquire chemoresistance and self-renewal in the tumor microenvironment. Glucose-regulated protein 78 (GRP78) is a biomarker for gastric cancer and is involved in cancer stemness. By inducing cancer stemness in various types of cancer, the polariza...

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Detalles Bibliográficos
Autores principales: Chen, Jen-Lung, Tai, Yun-Shen, Tsai, Hsin-Yi, Hsieh, Chia-Yuan, Chen, Chun-Lin, Liu, Chung-Jung, Wu, Deng-Chyang, Huang, Yaw-Bin, Lin, Ming-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9964887/
https://www.ncbi.nlm.nih.gov/pubmed/36838713
http://dx.doi.org/10.3390/molecules28041725