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Cancer-Specific Delivery of Proteolysis-Targeting Chimeras (PROTACs) and Their Application to Cancer Immunotherapy

Proteolysis-targeting chimeras (PROTACs) are rapidly emerging as a potential therapeutic strategy for cancer therapy by inducing the degradation of tumor-overexpressing oncogenic proteins. They can specifically catalyze the degradation of target oncogenic proteins by recruiting E3 ligases and utiliz...

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Detalles Bibliográficos
Autores principales: Moon, Yujeong, Jeon, Seong Ik, Shim, Man Kyu, Kim, Kwangmeyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965039/
https://www.ncbi.nlm.nih.gov/pubmed/36839734
http://dx.doi.org/10.3390/pharmaceutics15020411