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Development of a Novel Anti-CD44 Variant 6 Monoclonal Antibody C(44)Mab-9 for Multiple Applications against Colorectal Carcinomas

CD44 is a cell surface glycoprotein, and its isoforms are produced by the alternative splicing with the standard and variant exons. The CD44 variant exon-containing isoforms (CD44v) are overexpressed in carcinomas. CD44v6 is one of the CD44v, and its overexpression predicts poor prognosis in colorec...

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Detalles Bibliográficos
Autores principales: Ejima, Ryo, Suzuki, Hiroyuki, Tanaka, Tomohiro, Asano, Teizo, Kaneko, Mika K., Kato, Yukinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965047/
https://www.ncbi.nlm.nih.gov/pubmed/36835416
http://dx.doi.org/10.3390/ijms24044007