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MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength

Synaptic plasticity depends on rapid experience-dependent changes in the number of neurotransmitter receptors. Previously, we demonstrated that motor-mediated transport of AMPA receptors (AMPARs) to and from synapses is a critical determinant of synaptic strength. Here, we describe two convergent si...

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Detalles Bibliográficos
Autores principales: Hoerndli, Frédéric J., Brockie, Penelope J., Wang, Rui, Mellem, Jerry E., Kallarackal, Angy, Doser, Rachel L., Pierce, Dayton M., Madsen, David M., Maricq, Andres V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965202/
https://www.ncbi.nlm.nih.gov/pubmed/35354038
http://dx.doi.org/10.1016/j.celrep.2022.110577