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MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength
Synaptic plasticity depends on rapid experience-dependent changes in the number of neurotransmitter receptors. Previously, we demonstrated that motor-mediated transport of AMPA receptors (AMPARs) to and from synapses is a critical determinant of synaptic strength. Here, we describe two convergent si...
Autores principales: | Hoerndli, Frédéric J., Brockie, Penelope J., Wang, Rui, Mellem, Jerry E., Kallarackal, Angy, Doser, Rachel L., Pierce, Dayton M., Madsen, David M., Maricq, Andres V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965202/ https://www.ncbi.nlm.nih.gov/pubmed/35354038 http://dx.doi.org/10.1016/j.celrep.2022.110577 |
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