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Antiviral Mechanism of Virucidal Sialic Acid Modified Cyclodextrin

We have reported that CD-6′SLN [6-sialyllactosamine (6′SLN)-modified β-cyclodextrin (CD)] can be a potential anti-influenza drug because it irreversibly deactivates virions. Indeed, in vivo, CD-6′SLN improved mice survival in an H1N1 infection model even when administered 24 h post-infection. Althou...

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Detalles Bibliográficos
Autores principales: Zhu, Yong, Sysoev, Andrey A., Silva, Paulo H. Jacob, Batista, Marine, Stellacci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965221/
https://www.ncbi.nlm.nih.gov/pubmed/36839904
http://dx.doi.org/10.3390/pharmaceutics15020582