Diversity of Structural, Dynamic, and Environmental Effects Explain a Distinctive Functional Role of Transmembrane Domains in the Insulin Receptor Subfamily

Human InsR, IGF1R, and IRR receptor tyrosine kinases (RTK) of the insulin receptor subfamily play an important role in signaling pathways for a wide range of physiological processes and are directly associated with many pathologies, including neurodegenerative diseases. The disulfide-linked dimeric...

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Detalles Bibliográficos
Autores principales: Bershatsky, Yaroslav V., Kuznetsov, Andrey S., Idiatullina, Aisha R., Bocharova, Olga V., Dolotova, Sofya M., Gavrilenkova, Alina A., Serova, Oxana V., Deyev, Igor E., Rakitina, Tatiana V., Zangieva, Olga T., Pavlov, Konstantin V., Batishchev, Oleg V., Britikov, Vladimir V., Usanov, Sergey A., Arseniev, Alexander S., Efremov, Roman G., Bocharov, Eduard V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965288/
https://www.ncbi.nlm.nih.gov/pubmed/36835322
http://dx.doi.org/10.3390/ijms24043906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965288/
https://www.ncbi.nlm.nih.gov/pubmed/36835322
http://dx.doi.org/10.3390/ijms24043906

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