Insights into the Transport Cycle of LAT1 and Interaction with the Inhibitor JPH203

The large Amino Acid Transporter 1 (LAT1) is an interesting target in drug discovery since this transporter is overexpressed in several human cancers. Furthermore, due to its location in the blood-brain barrier (BBB), LAT1 is interesting for delivering pro-drugs to the brain. In this work, we focuse...

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Detalles Bibliográficos
Autores principales: Brunocilla, Chiara, Console, Lara, Rovella, Filomena, Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965313/
https://www.ncbi.nlm.nih.gov/pubmed/36835453
http://dx.doi.org/10.3390/ijms24044042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965313/
https://www.ncbi.nlm.nih.gov/pubmed/36835453
http://dx.doi.org/10.3390/ijms24044042

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