A Proposed Methodology to Deal with the Impact of In Vitro Cellular Matrix on the Analytical Performances of a Targeted Metabolomic LC-HRMS Method

Performances of metabolomic methods have been widely studied on biological matrices such as serum, plasma, and urine; but much less on in vitro cell extracts. While the impact of cell culture and sample preparation on results are well-described, the specific effect of the in vitro cellular matrix on...

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Detalles Bibliográficos
Autores principales: Guitton, Jérôme, Gavotto, Floriane, Cros-Perrial, Emeline, Jordheim, Lars Petter, Machon, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965333/
https://www.ncbi.nlm.nih.gov/pubmed/36835182
http://dx.doi.org/10.3390/ijms24043770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965333/
https://www.ncbi.nlm.nih.gov/pubmed/36835182
http://dx.doi.org/10.3390/ijms24043770

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