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Identification of SARS-CoV-2 Main Protease (Mpro) Cleavage Sites Using Two-Dimensional Electrophoresis and In Silico Cleavage Site Prediction

The main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a crucial role in its life cycle. The Mpro-mediated limited proteolysis of the viral polyproteins is necessary for the replication of the virus, and cleavage of the host proteins of the infected cells may...

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Detalles Bibliográficos
Autores principales: Miltner, Noémi, Kalló, Gergő, Csősz, Éva, Miczi, Márió, Nagy, Tibor, Mahdi, Mohamed, Mótyán, János András, Tőzsér, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965337/
https://www.ncbi.nlm.nih.gov/pubmed/36834648
http://dx.doi.org/10.3390/ijms24043236