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Targeting Mcl-1 Degradation by Bergenin Inhibits Tumorigenesis of Colorectal Cancer Cells

Myeloid leukemia 1 (Mcl-1) is frequently overexpressed in human malignancies and emerged as a promising drug target. In this study, we verified the inhibitory effect of bergenin on colorectal cancer cells both in vivo and in vitro. In an in vitro setting, bergenin significantly reduced the viability...

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Detalles Bibliográficos
Autores principales: Gan, Yu, Li, Xiaoying, Han, Shuangze, Zhou, Li, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965350/
https://www.ncbi.nlm.nih.gov/pubmed/37259388
http://dx.doi.org/10.3390/ph16020241