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Mineralocorticoid Receptor Antagonism Attenuates Multiple Organ Failure after Renal Ischemia and Reperfusion in Mice

Renal ischemia reperfusion (IR) injury is a major cause of acute kidney injury (AKI) that is often complicated by multiple organ failure of the liver and intestine. The mineralocorticoid receptor (MR) is activated in patients with renal failure associated with glomerular and tubular damage. We thus...

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Detalles Bibliográficos
Autores principales: Park, Eun Jung, Je, Jihyun, Dusabimana, Theodomir, Yun, Seung Pil, Kim, Hye Jung, Kim, Hwajin, Park, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965387/
https://www.ncbi.nlm.nih.gov/pubmed/36834824
http://dx.doi.org/10.3390/ijms24043413