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An Unexpected Enzyme in Vascular Smooth Muscle Cells: Angiotensin II Upregulates Cholesterol-25-Hydroxylase Gene Expression

Angiotensin II (AngII) is a vasoactive peptide hormone, which, under pathological conditions, contributes to the development of cardiovascular diseases. Oxysterols, including 25-hydroxycholesterol (25-HC), the product of cholesterol-25-hydroxylase (CH25H), also have detrimental effects on vascular h...

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Detalles Bibliográficos
Autores principales: Kovács, Kinga Bernadett, Szalai, Laura, Szabó, Pál, Gém, Janka Borbála, Barsi, Szilvia, Szalai, Bence, Perey-Simon, Bernadett, Turu, Gábor, Tóth, András Dávid, Várnai, Péter, Hunyady, László, Balla, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965395/
https://www.ncbi.nlm.nih.gov/pubmed/36835391
http://dx.doi.org/10.3390/ijms24043968