Cargando…

PLGA Nanoparticles Loaded with Sorafenib Combined with Thermosensitive Hydrogel System and Microwave Hyperthermia for Multiple Sensitized Radiotherapy

Hypoxia is typically the leading cause of radiotherapy (RT) resistance in solid tumors, and glutathione (GSH) overexpression in tumor cells is a potent antioxidant mechanism that protects tumor cells from radiation damage. Herein, we developed a sorafenib (SFN) loaded-PLGA hydrogel system (SPH) in c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ziqi, Liu, Bo, Tu, Jingyao, Xiang, Jingfeng, Xiong, Hui, Wu, Yue, Ding, Shuaijie, Zhu, Daoming, Zhu, Dongyong, Liu, Fei, Hu, Guangyuan, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965455/
https://www.ncbi.nlm.nih.gov/pubmed/36839808
http://dx.doi.org/10.3390/pharmaceutics15020487