Cargando…

PLGA Nanoparticles Loaded with Sorafenib Combined with Thermosensitive Hydrogel System and Microwave Hyperthermia for Multiple Sensitized Radiotherapy

Hypoxia is typically the leading cause of radiotherapy (RT) resistance in solid tumors, and glutathione (GSH) overexpression in tumor cells is a potent antioxidant mechanism that protects tumor cells from radiation damage. Herein, we developed a sorafenib (SFN) loaded-PLGA hydrogel system (SPH) in c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ziqi, Liu, Bo, Tu, Jingyao, Xiang, Jingfeng, Xiong, Hui, Wu, Yue, Ding, Shuaijie, Zhu, Daoming, Zhu, Dongyong, Liu, Fei, Hu, Guangyuan, Yuan, Xianglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965455/ https://www.ncbi.nlm.nih.gov/pubmed/36839808 http://dx.doi.org/10.3390/pharmaceutics15020487

Ejemplares similares

Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy
por: Heine, Sonja, et al.
Publicado: (2022)

Doxorubicin and CD-CUR inclusion complex co-loaded in thermosensitive hydrogel PLGA-PEG-PLGA localized administration for osteosarcoma
por: Yang, Zhiming, et al.
Publicado: (2020)

Intracranial In Situ Thermosensitive Hydrogel Delivery of Temozolomide Accomplished by PLGA–PEG–PLGA Triblock Copolymer Blending for GBM Treatment
por: Gu, Weinan, et al.
Publicado: (2022)

CuS nanoparticles and camptothecin co-loaded thermosensitive injectable hydrogel with self-supplied H(2)O(2) for enhanced chemodynamic therapy
por: Tang, Wenxue, et al.
Publicado: (2022)

Thermosensitive Nanosystems Associated with Hyperthermia for Cancer Treatment
por: Pereira Gomes, Isabela, et al.
Publicado: (2019)

Transferrin as a thermosensitizer in radiofrequency hyperthermia for cancer treatment
por: Chung, Hea-Jong, et al.
Publicado: (2018)

Investigation of Particle Accumulation, Chemosensitivity and Thermosensitivity for Effective Solid Tumor Therapy Using Thermosensitive Liposomes and Hyperthermia
por: Lokerse, Wouter J.M., et al.
Publicado: (2016)

Magnetic Nanoparticles Coated with a Thermosensitive Polymer with Hyperthermia Properties
por: Reyes-Ortega, Felisa, et al.
Publicado: (2017)

Triggered radiosensitizer delivery using thermosensitive liposomes and hyperthermia improves efficacy of radiotherapy: An in vitro proof of concept study
por: Besse, Helena C., et al.
Publicado: (2018)

Hyperthermia and Thermosensitive Liposomes for Improved Delivery of Chemotherapeutic Drugs to Solid Tumors
por: Koning, Gerben A., et al.
Publicado: (2010)

Treatment of critically sized femoral defects with recombinant BMP-2 delivered by a modified mPEG-PLGA biodegradable thermosensitive hydrogel
por: Peng, Kuo-Ti, et al.
Publicado: (2016)

A Tailored Thermosensitive PLGA-PEG-PLGA/Emulsomes Composite for Enhanced Oxcarbazepine Brain Delivery via the Nasal Route
por: El-Zaafarany, Ghada M., et al.
Publicado: (2018)

Dual Drug Delivery of Sorafenib and Doxorubicin from PLGA and PEG-PLGA Polymeric Nanoparticles
por: Babos, György, et al.
Publicado: (2018)

Wettability of HPMC/PEG/CS Thermosensitive Porous Hydrogels
por: Ma, Li, et al.
Publicado: (2023)

Targeting Chemotherapy to Solid Tumors with Long‐circulating Thermosensitive Liposomes and Local Hyperthermia
por: Ishida, Osamu, et al.
Publicado: (2000)

Thermosensitive Nanocomposite Hydrogels for Intravitreal Delivery of Cefuroxime
por: Sapino, Simona, et al.
Publicado: (2019)

Research Progress of Thermosensitive Hydrogel in Tumor Therapeutic
por: Ma, Nian, et al.
Publicado: (2021)

Thermosensitive Hydrogels and Advances in Their Application in Disease Therapy
por: Fan, Ranran, et al.
Publicado: (2022)

Hyperthermia, Radiotherapy
Publicado: (1998)

Silver sulfadiazine nanosuspension-loaded thermosensitive hydrogel as a topical antibacterial agent
por: Liu, Xiaoya, et al.
Publicado: (2018)

Release of a Wound-Healing Agent from PLGA Microspheres in a Thermosensitive Gel
por: Machado, H. A., et al.
Publicado: (2013)

Facile Assembly of Thermosensitive Liposomes for Active Targeting Imaging and Synergetic Chemo-/Magnetic Hyperthermia Therapy
por: An, Yanli, et al.
Publicado: (2021)

Co-delivery of metformin and levofloxacin hydrochloride using biodegradable thermosensitive hydrogel for the treatment of corneal neovascularization
por: Liu, Dong, et al.
Publicado: (2019)

The Effect of the Thermosensitive Biodegradable PLGA–PEG–PLGA Copolymer on the Rheological, Structural and Mechanical Properties of Thixotropic Self-Hardening Tricalcium Phosphate Cement
por: Vojtova, Lucy, et al.
Publicado: (2019)

An Injectable Hydrogel for Enhanced FeGA-Based Chemodynamic Therapy by Increasing Intracellular Acidity
por: Zeng, Wen, et al.
Publicado: (2021)

POSS-enhanced thermosensitive hybrid hydrogels for cell adhesion and detachment
por: Tong, Yudong, et al.
Publicado: (2018)

Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes
Publicado: (2021)

Iron oxide nanoflowers encapsulated in thermosensitive fluorescent liposomes for hyperthermia treatment of lung adenocarcinoma
por: Theodosiou, Maria, et al.
Publicado: (2022)

A Novel Approach on Microwave Hyperthermia
por: Altintas, Gulsah, et al.
Publicado: (2021)

Treatment outcomes of injectable thermosensitive hydrogel containing bevacizumab in intervertebral disc degeneration
por: Chen, Qian, et al.
Publicado: (2022)

Novel thermosensitive hydrogel for preventing formation of abdominal adhesions
por: Gao, Xiang, et al.
Publicado: (2013)

Thermosensitive hydrogels deliver bioactive protein to the vaginal wall
por: Good, Meadow M., et al.
Publicado: (2017)

Development of Thermosensitive and Mucoadhesive Hydrogel for Buccal Delivery of (S)-Ketamine
por: Thouvenin, Agathe, et al.
Publicado: (2022)

Cu-doped polypyrrole hydrogel with tumor catalyst activity for NIR-II thermo-radiotherapy
por: Wang, Shile, et al.
Publicado: (2023)

Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib
por: Zheng, Ning, et al.
Publicado: (2019)

Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats
por: Rong, Xianfang, et al.
Publicado: (2018)

Experimental Study on Thermosensitive Hydrogel Used to Extinguish Class A Fire
por: Ma, Li, et al.
Publicado: (2021)

Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel
por: Wang, Kun, et al.
Publicado: (2023)

Pharmacokinetics, Tissue Distribution and Therapeutic Effect of Cationic Thermosensitive Liposomal Doxorubicin Upon Mild Hyperthermia
por: Dicheva, Bilyana M., et al.
Publicado: (2015)

Assessment of Intratumoral Doxorubicin Penetration after Mild Hyperthermia-Mediated Release from Thermosensitive Liposomes
por: Derieppe, Marc, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0bgh67n9fd0pjch2n38bt0ub46