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An Efficient Peptidomics Screening for Exogenous Substrates and Inhibitory Peptides of the Dipeptidase ACE from Milk Hydrolysate

The dipeptidase angiotensin-I-converting enzyme (ACE) pre-incubation, liquid chromatography- mass spectrometry (LC-MS), and stable-isotope labeling were integrated for an efficient screening of ACE’s exogenous substrates from milk hydrolysate. Using this approach, 31 substrates were readily identifi...

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Detalles Bibliográficos
Autores principales: Huang, Ju-Hsuan, Nong, Nhung Thi Phuong, Hsu, Jue-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965520/
https://www.ncbi.nlm.nih.gov/pubmed/36839747
http://dx.doi.org/10.3390/pharmaceutics15020425