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Solute Carrier Family 29A1 Mediates In Vitro Resistance to Azacitidine in Acute Myeloid Leukemia Cell Lines

Azacitidine (AZA) is commonly used hypomethylating agent for higher risk myelodysplastic syndromes and acute myeloid leukemia (AML). Although some patients achieve remission, eventually most patients fail AZA therapy. Comprehensive analysis of intracellular uptake and retention (IUR) of carbon-label...

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Detalles Bibliográficos
Autores principales: Kutyna, Monika M., Loone, Sophie, Saunders, Verity A., White, Deborah L., Kok, Chung H., Hiwase, Devendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965596/
https://www.ncbi.nlm.nih.gov/pubmed/36834962
http://dx.doi.org/10.3390/ijms24043553