Vx-809, a CFTR Corrector, Acts through a General Mechanism of Protein Folding and on the Inflammatory Process

Correct protein folding is the basis of cellular well-being; thus, accumulation of misfolded proteins within the endoplasmic reticulum (ER) leads to an imbalance of homeostasis that causes stress to the ER. Various studies have shown that protein misfolding is a significant factor in the etiology of...

Descripción completa

Detalles Bibliográficos
Autores principales: Pecoraro, Michela, Serra, Adele, Pascale, Maria, Franceschelli, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965627/
https://www.ncbi.nlm.nih.gov/pubmed/36835664
http://dx.doi.org/10.3390/ijms24044252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965627/
https://www.ncbi.nlm.nih.gov/pubmed/36835664
http://dx.doi.org/10.3390/ijms24044252

Ejemplares similares