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Vx-809, a CFTR Corrector, Acts through a General Mechanism of Protein Folding and on the Inflammatory Process
Correct protein folding is the basis of cellular well-being; thus, accumulation of misfolded proteins within the endoplasmic reticulum (ER) leads to an imbalance of homeostasis that causes stress to the ER. Various studies have shown that protein misfolding is a significant factor in the etiology of...
Autores principales: | Pecoraro, Michela, Serra, Adele, Pascale, Maria, Franceschelli, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965627/ https://www.ncbi.nlm.nih.gov/pubmed/36835664 http://dx.doi.org/10.3390/ijms24044252 |
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