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In Candida glabrata, ERMES Component GEM1 Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility

Mitochondrial dysfunction or morphological abnormalities in human pathogenic fungi are known to contribute to azole resistance; however, the underlying molecular mechanisms are unknown. In this study, we investigated the link between mitochondrial morphology and azole resistance in Candida glabrata,...

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Detalles Bibliográficos
Autores principales: Okamoto, Michiyo, Nakano, Keiko, Takahashi-Nakaguchi, Azusa, Sasamoto, Kaname, Yamaguchi, Masashi, Teixeira, Miguel Cacho, Chibana, Hiroji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965728/
https://www.ncbi.nlm.nih.gov/pubmed/36836353
http://dx.doi.org/10.3390/jof9020240