Small-Molecule Inhibition of MuRF1 Prevents Early Disuse-Induced Diaphragmatic Dysfunction and Atrophy

In clinical conditions such as diaphragm paralysis or mechanical ventilation, disuse-induced diaphragmatic dysfunction (DIDD) is a condition that poses a threat to life. MuRF1 is a key E3-ligase involved in regulating skeletal muscle mass, function, and metabolism, which contributes to the onset of...

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Detalles Bibliográficos
Autores principales: Ribeiro, Fernando, Alves, Paula K. N., Bechara, Luiz R. G., Ferreira, Julio C. B., Labeit, Siegfried, Moriscot, Anselmo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965746/
https://www.ncbi.nlm.nih.gov/pubmed/36835047
http://dx.doi.org/10.3390/ijms24043637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965746/
https://www.ncbi.nlm.nih.gov/pubmed/36835047
http://dx.doi.org/10.3390/ijms24043637

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