Investigation of Multi-Subunit Mycobacterium tuberculosis DNA-Directed RNA Polymerase and Its Rifampicin Resistant Mutants

Emerging Mycobacterium tuberculosis (Mtb) resistant strains have continued to limit the efficacies of existing antitubercular therapies. More specifically, mutations in the RNA replicative machinery of Mtb, RNA polymerase (RNAP), have been widely linked to rifampicin (RIF) resistance, which has led...

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Detalles Bibliográficos
Autores principales: Monama, Mokgerwa Zacharia, Olotu, Fisayo, Tastan Bishop, Özlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965755/
https://www.ncbi.nlm.nih.gov/pubmed/36834726
http://dx.doi.org/10.3390/ijms24043313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965755/
https://www.ncbi.nlm.nih.gov/pubmed/36834726
http://dx.doi.org/10.3390/ijms24043313

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