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Needle-Free Devices and CpG-Adjuvanted DNA Improve Anti-HIV Antibody Responses of Both DNA and Modified Vaccinia Ankara-Vectored Candidate Vaccines

The combination of mosaic Gag and CAP256 envelope in an HIV vaccine regimen comprising DNA prime and modified vaccinia Ankara (MVA) boost followed by protein boost has previously been shown to generate robust autologous Tier 2 neutralizing antibodies (nAbs) in rabbits. Further refinements of this st...

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Detalles Bibliográficos
Autores principales: Chapman, Rosamund, van Diepen, Michiel, Douglass, Nicola, Hermanus, Tandile, Moore, Penny L., Williamson, Anna-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965773/
https://www.ncbi.nlm.nih.gov/pubmed/36851255
http://dx.doi.org/10.3390/vaccines11020376