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Synthesis of 6-Alkynylated Purine-Containing DNA via On-Column Sonogashira Coupling and Investigation of Their Base-Pairing Properties

Synthetic unnatural base pairs have been proven to be attractive tools for the development of DNA-based biotechnology. Our group has very recently reported on alkynylated purine–pyridazine pairs, which exhibit selective and stable base-pairing via hydrogen bond formation between pseudo-nucleobases i...

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Detalles Bibliográficos
Autores principales: Okamura, Hidenori, Trinh, Giang Hoang, Dong, Zhuoxin, Fan, Wenjue, Nagatsugi, Fumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965804/
https://www.ncbi.nlm.nih.gov/pubmed/36838761
http://dx.doi.org/10.3390/molecules28041766