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The BNT162b2 mRNA COVID-19 Vaccine Increases the Contractile Sensitivity to Histamine and Parasympathetic Activation in a Human Ex Vivo Model of Severe Eosinophilic Asthma

The BNT162b2 COVID-19 vaccine is composed of lipid-nanoparticles (LNP) containing the mRNA that encodes for SARS-CoV-2 spike glycoprotein. Bronchospasm has been reported as an early reaction after COVID-19 mRNA vaccines in asthmatic patients. The aim of this study was to investigate the acute impact...

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Detalles Bibliográficos
Autores principales: Calzetta, Luigino, Chetta, Alfredo, Aiello, Marina, Frizzelli, Annalisa, Ora, Josuel, Melis, Enrico, Facciolo, Francesco, Ippoliti, Lorenzo, Magrini, Andrea, Rogliani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965850/
https://www.ncbi.nlm.nih.gov/pubmed/36851160
http://dx.doi.org/10.3390/vaccines11020282