Cyclodextrin-Based Nanoparticles for Delivery of Antisense Oligonucleotides Targeting Huntingtin

Huntington’s disease (HD) is a progressive inherited neurodegenerative disease caused by a CAG repeat expansion in the huntingtin gene, which is translated into the pathologic mutant huntingtin (mHTT) protein. Despite the great potential of HTT lowering strategies and the numerous antisense oligonuc...

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Detalles Bibliográficos
Autores principales: Mendonça, Monique C. P., Sun, Yao, Cronin, Michael F., Lindsay, Andrew J., Cryan, John F., O’Driscoll, Caitriona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965918/
https://www.ncbi.nlm.nih.gov/pubmed/36839842
http://dx.doi.org/10.3390/pharmaceutics15020520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965918/
https://www.ncbi.nlm.nih.gov/pubmed/36839842
http://dx.doi.org/10.3390/pharmaceutics15020520

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