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Cyclodextrin-Based Nanoparticles for Delivery of Antisense Oligonucleotides Targeting Huntingtin

Huntington’s disease (HD) is a progressive inherited neurodegenerative disease caused by a CAG repeat expansion in the huntingtin gene, which is translated into the pathologic mutant huntingtin (mHTT) protein. Despite the great potential of HTT lowering strategies and the numerous antisense oligonuc...

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Detalles Bibliográficos
Autores principales:	Mendonça, Monique C. P., Sun, Yao, Cronin, Michael F., Lindsay, Andrew J., Cryan, John F., O’Driscoll, Caitriona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9965918/ https://www.ncbi.nlm.nih.gov/pubmed/36839842 http://dx.doi.org/10.3390/pharmaceutics15020520

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