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Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Here, we investigate the potential of CD70 co-expression during viral vector boost vaccination to improve an antigen-specific T cell response. To determine the chance of activating antigen-specific T cells by CD70, we used the HBV core antigen as a model antigen in a heterologous protein-prime, Modi...

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Detalles Bibliográficos
Autores principales: Stephan, Ann-Sophie, Kosinska, Anna D., Mück-Häusl, Martin, Muschaweckh, Andreas, Jäger, Clemens, Röder, Natalie, Heikenwälder, Mathias, Dembek, Claudia, Protzer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966001/
https://www.ncbi.nlm.nih.gov/pubmed/36851121
http://dx.doi.org/10.3390/vaccines11020245