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Aggregation of Disordered Proteins Associated with Neurodegeneration

Cellular deposition of protein aggregates, one of the hallmarks of neurodegeneration, disrupts cellular functions and leads to neuronal death. Mutations, posttranslational modifications, and truncations are common molecular underpinnings in the formation of aberrant protein conformations that seed a...

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Detalles Bibliográficos
Autores principales: Tsoi, Phoebe S., Quan, My Diem, Ferreon, Josephine C., Ferreon, Allan Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966039/
https://www.ncbi.nlm.nih.gov/pubmed/36834792
http://dx.doi.org/10.3390/ijms24043380