Semi-Synthetic Dihydrotestosterone Derivatives Modulate Inherent Multidrug Resistance and Sensitize Colon Cancer Cells to Chemotherapy

Multidrug resistance (MDR) is a serious hurdle to successful cancer therapy. Here, we examined the efficiency of novel semi-synthetic dihydrotestosterone derivatives, more specifically androstano-arylpyrimidines in inhibiting the efflux activity of ATP-binding cassette (ABC) transporters and sensiti...

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Detalles Bibliográficos
Autores principales: Nagy, Ferenc István, Adamecz, Dóra Izabella, Baji, Ádám, Kiricsi, Ágnes, Huliák, Ildikó, Rónavári, Andrea, Kónya, Zoltán, Frank, Éva, Gopisetty, Mohana Krishna, Kiricsi, Mónika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966060/
https://www.ncbi.nlm.nih.gov/pubmed/36839907
http://dx.doi.org/10.3390/pharmaceutics15020584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966060/
https://www.ncbi.nlm.nih.gov/pubmed/36839907
http://dx.doi.org/10.3390/pharmaceutics15020584

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