A Pentavalent Shigella flexneri LPS-Based Vaccine Candidate Is Safe and Immunogenic in Animal Models

A multivalent vaccine is much needed to achieve protection against predominant Shigella serotypes. Recently, we demonstrated the clinical applicability and immunogenic potential of tri-acylated S. flexneri 2a lipopolysaccharide (Ac(3)-S-LPS). Using a similar approach, we designed a pentavalent LPS c...

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Detalles Bibliográficos
Autores principales: Ledov, Vladimir A., Golovina, Marina E., Alkhazova, Biana I., Lvov, Vyacheslav L., Kovalchuk, Alexander L., Aparin, Petr G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966156/
https://www.ncbi.nlm.nih.gov/pubmed/36851223
http://dx.doi.org/10.3390/vaccines11020345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966156/
https://www.ncbi.nlm.nih.gov/pubmed/36851223
http://dx.doi.org/10.3390/vaccines11020345

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