Paracrine Effects of Renal Proximal Tubular Epithelial Cells on Podocyte Injury under Hypoxic Conditions Are Mediated by Arginase-II and TGF-β1

Hypoxia is an important risk for renal disease. The mitochondrial enzyme arginase-II (Arg-II) is expressed and/or induced by hypoxia in proximal tubular epithelial cells (PTECs) and in podocytes, leading to cellular damage. Because PTECs are vulnerable to hypoxia and located in proximity to podocyte...

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Detalles Bibliográficos
Autores principales: Ma, Yiqiong, Potenza, Duilio Michele, Ajalbert, Guillaume, Brenna, Andrea, Zhu, Cui, Ming, Xiu-Fen, Yang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966309/
https://www.ncbi.nlm.nih.gov/pubmed/36835007
http://dx.doi.org/10.3390/ijms24043587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966309/
https://www.ncbi.nlm.nih.gov/pubmed/36835007
http://dx.doi.org/10.3390/ijms24043587

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