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Inguinal Fat Compensates Whole Body Metabolic Functionality in Partially Lipodystrophic Mice with Reduced PPARγ Expression

Peroxisome proliferator-activated receptor γ (PPARγ) gene mutations in humans and mice lead to whole-body insulin resistance and partial lipodystrophy. It is unclear whether preserved fat depots in partial lipodystrophy are beneficial for whole-body metabolic homeostasis. We analyzed the insulin res...

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Detalles Bibliográficos
Autores principales: Chang, Cherng-Shyang, Yu, Shang-Shiuan, Ho, Li-Chun, Chao, Shu-Hsin, Chou, Ting-Yu, Shao, Ai-Ning, Kao, Ling-Zhen, Chang, Chia-Yu, Chen, Yu-Hsin, Wu, Ming-Shan, Tsai, Pei-Jane, Maeda, Nobuyo, Tsai, Yau-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966317/
https://www.ncbi.nlm.nih.gov/pubmed/36835312
http://dx.doi.org/10.3390/ijms24043904