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Generation of Transgenic Sperm Expressing GFP by Lentivirus Transduction of Spermatogonial Stem Cells In Vivo in Cynomolgus Monkeys

SIMPLE SUMMARY: Gene editing technology is expected to be an effective way to establish animal models of human diseases. Using spermatogonial stem cells and sperm as gene editing objects is simple to operate. However, there has been no research on gene editing of spermatogonial stem cells to obtain...

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Detalles Bibliográficos
Autores principales: Wang, Shengnan, Duan, Yanchao, Chen, Bingbing, Qiu, Shuai, Huang, Tianzhuang, Si, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966439/
https://www.ncbi.nlm.nih.gov/pubmed/36851408
http://dx.doi.org/10.3390/vetsci10020104