Cargando…
Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML
In vivo models of acute myeloid leukemia (AML) are low throughput, and standard liquid culture models fail to recapitulate the mechanical and biochemical properties of the extracellular matrix-rich protective bone marrow niche that contributes to drug resistance. Candidate drug discovery in AML requ...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966469/ https://www.ncbi.nlm.nih.gov/pubmed/36835644 http://dx.doi.org/10.3390/ijms24044235 |