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Memory Precursors and Short-Lived Effector T cell Subsets Have Different Sensitivities to TGFβ

After exposure to an antigen, CD8 T cells reach a decision point about their fate: to become either short-lived effector cells (SLECs) or memory progenitor effector cells (MPECs). SLECs are specialized in providing an immediate effector function but have a shorter lifespan and lower proliferative ca...

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Detalles Bibliográficos
Autores principales: O’Sullivan, Jeremy A., Kohlhapp, Frederick J., Zloza, Andrew, Plaza-Rojas, Lourdes, Burke, Brianna, Dulin, Nickolai O., Guevara-Patiño, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966622/
https://www.ncbi.nlm.nih.gov/pubmed/36835342
http://dx.doi.org/10.3390/ijms24043930