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Lactose and Galactose Promote the Crystallization of Human Galectin-10

Galectin-10 (Gal-10) forms Charcot–Leyden crystals (CLCs), which play a key role in the symptoms of asthma and allergies and some other diseases. Gal-10 has a carbohydrate-binding site; however, neither the Gal-10 dimer nor the CLCs can bind sugars. To investigate the monomer–dimer equilibrium of Ga...

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Detalles Bibliográficos
Autores principales: Fu, Yu-Fan, Jiang, Si-Cong, Zhang, Zhong-Wei, Yang, Xin-Yue, Li, Zi-Lin, Hu, Jing, Yuan, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966682/
https://www.ncbi.nlm.nih.gov/pubmed/36838965
http://dx.doi.org/10.3390/molecules28041979