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Impact of Leucine and Magnesium Stearate on the Physicochemical Properties and Aerosolization Behavior of Wet Milled Inhalable Ibuprofen Microparticles for Developing Dry Powder Inhaler Formulation

This study investigated the development and characterization of leucine and magnesium stearate (MgSt) embedded wet milled inhalable ibuprofen (IBF) dry powder inhaler (DPI) formulations. IBF microparticles were prepared by a wet milling homogenization process and were characterized by SEM, FTIR, DSC...

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Detalles Bibliográficos
Autores principales: Sharif, Shahjabeen, Muneer, Saiqa, Izake, Emad L., Islam, Nazrul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966768/
https://www.ncbi.nlm.nih.gov/pubmed/36839997
http://dx.doi.org/10.3390/pharmaceutics15020674