Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice

Patients with inactive thyroid hormone (TH) transporter MCT8 display intellectual disability due to compromised central TH transport and action. As a therapeutic strategy, application of thyromimetic, MCT8-independent compounds Triac (3,5,3′-triiodothyroacetic acid), and Ditpa (3,5-diiodo-thyropropi...

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Detalles Bibliográficos
Autores principales: Chen, Jiesi, Salveridou, Eva, Liebmann, Lutz, Sundaram, Sivaraj M., Doycheva, Denica, Markova, Boyka, Hübner, Christian A., Boelen, Anita, Visser, W. Edward, Heuer, Heike, Mayerl, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966820/
https://www.ncbi.nlm.nih.gov/pubmed/36834863
http://dx.doi.org/10.3390/ijms24043452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966820/
https://www.ncbi.nlm.nih.gov/pubmed/36834863
http://dx.doi.org/10.3390/ijms24043452

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