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Epigenetic Regulation of Driver Genes in Testicular Tumorigenesis

In testicular germ cell tumor type II (TGCT), a seminoma subtype expresses an induced pluripotent stem cell (iPSC) panel with four upregulated genes, OCT4/POU5F1, SOX17, KLF4, and MYC, and embryonal carcinoma (EC) has four upregulated genes, OCT4/POU5F1, SOX2, LIN28, and NANOG. The EC panel can repr...

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Detalles Bibliográficos
Autores principales: von Eyben, Finn E., Kristiansen, Karsten, Kapp, Daniel S., Hu, Rong, Preda, Ovidiu, Nogales, Francisco F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966837/
https://www.ncbi.nlm.nih.gov/pubmed/36835562
http://dx.doi.org/10.3390/ijms24044148