Study of Genotoxicity, Activities on Caspase 8 and on the Stabilization of the Topoisomerase Complex of Isoeleutherin and Analogues

This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from Eleutherine plicata, using the micronucleus test and the impact of structural alterations on toxicity and molecular docking (topoisomerase II and DNA complex). The extra...

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Detalles Bibliográficos
Autores principales: de Albuquerque, Kelly Cristina Oliveira, Galucio, Natasha Costa da Rocha, Ferreira, Gleison Gonçalves, Quaresma, Ana Carolina Sousa, Vale, Valdicley Vieira, Bahia, Marcelo de Oliveira, Burbano, Rommel Mario Rodriguez, de Molfetta, Fábio Alberto, Percario, Sandro, Dolabela, Maria Fâni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966911/
https://www.ncbi.nlm.nih.gov/pubmed/36838618
http://dx.doi.org/10.3390/molecules28041630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966911/
https://www.ncbi.nlm.nih.gov/pubmed/36838618
http://dx.doi.org/10.3390/molecules28041630

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