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Naxitamab Activity in Neuroblastoma Cells Is Enhanced by Nanofenretinide and Nanospermidine

Neuroblastoma cells highly express the disialoganglioside GD2, a tumor-associated carbohydrate antigen, which is also expressed in neurons, skin melanocytes, and peripheral nerve fibers. Immunotherapy with monoclonal anti-GD2 antibodies has a proven efficacy in clinical trials and is included in the...

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Detalles Bibliográficos
Autores principales: Galassi, Lucrezia, Rossi, Martina, Lodeserto, Pietro, Lenzi, Monia, Borsetti, Francesca, Voltattorni, Manuela, Farruggia, Giovanna, Blasi, Paolo, Orienti, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966923/
https://www.ncbi.nlm.nih.gov/pubmed/36839972
http://dx.doi.org/10.3390/pharmaceutics15020648