Novel Hybrid Indole-Based Caffeic Acid Amide Derivatives as Potent Free Radical Scavenging Agents: Rational Design, Synthesis, Spectroscopic Characterization, In Silico and In Vitro Investigations

Antioxidant small molecules can prevent or delay the oxidative damage caused by free radicals. Herein, a structure-based hybridization of two natural antioxidants (caffeic acid and melatonin) afforded a novel hybrid series of indole-based amide analogues which was synthesized with potential antioxid...

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Detalles Bibliográficos
Autores principales: Elkamhawy, Ahmed, Oh, Na Kyoung, Gouda, Noha A., Abdellattif, Magda H., Alshammari, Saud O., Abourehab, Mohammed A. S., Alshammari, Qamar A., Belal, Amany, Kim, Minkyoung, Al-Karmalawy, Ahmed A., Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966950/
https://www.ncbi.nlm.nih.gov/pubmed/36837759
http://dx.doi.org/10.3390/metabo13020141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966950/
https://www.ncbi.nlm.nih.gov/pubmed/36837759
http://dx.doi.org/10.3390/metabo13020141

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