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ABCG5 and ABCG8 Are Involved in Vitamin K Transport

ATP-binding cassette protein G5 (ABCG5)/ABCG8 heterodimer exports cholesterol from cells, while Niemann–Pick C1-like 1 (NPC1L1) imports cholesterol and vitamin K. We examined whether ABCG5/ABCG8 transports vitamin K similar to NPC1L1. Since high concentrations of vitamin K(3) show cytotoxicity, the...

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Detalles Bibliográficos
Autores principales: Matsuo, Michinori, Ogata, Yutaka, Yamanashi, Yoshihide, Takada, Tappei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9966996/
https://www.ncbi.nlm.nih.gov/pubmed/36839356
http://dx.doi.org/10.3390/nu15040998