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Whole-Transcriptome Analysis Highlights Adenylyl Cyclase Toxins-Derived Modulation of NF-κB and ERK1/2 Pathways in Macrophages

Edema toxin (ET), one of the main toxic factors of Bacillus anthracis (B. anthracis), is a kind of potent adenylate cyclase (AC). B. anthracis has adapted to resist macrophage microbicidal mechanisms in part by secreting ET. To date, there is limited information on the pathogenic mechanisms used by...

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Detalles Bibliográficos
Autores principales: Zhao, Taoran, Li, Ruihua, Qian, Mengyin, Wang, Meirong, Zhang, Xiaozheng, Wang, Yuhan, Zhao, Xinghui, Xie, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967024/
https://www.ncbi.nlm.nih.gov/pubmed/36828453
http://dx.doi.org/10.3390/toxins15020139